Patients with chilblains are generally prescribed OTC medications purchased at a pharmacy. The condition is treated symptomatically using certain medications.During the diagnostic process, your doctor will diagnose or examine your skin condition.Further tests like skin biopsy may be suggested to rule out other causes for your signs and symptoms.The first line of treatment includes measures to keep  Read More

De Sanctis-Cacchione syndrome is an extremely rare genetic condition that affects the brain and nervous system development. It is distinguished by cognitive impairment, developmental delays, and skin abnormalities (Xeroderma pigmentosum). The syndrome is named after the Italian doctors who described it for the first time in the early twentieth century. Due to its extreme rarity, hardly 200 cases are reported, and it tends to a  Read More

Deciduous skin is defined as the periodic, continuous, or seasonal peeling or shedding of the epidermal skin layer considering a generalized distribution.Deciduous skin is also referred to as the peeling skin syndrome (PSS), which is a rare autosomal recessive form of ichthyosis.This is clinically characterized by asymptomatic, superficial, and spontaneous peeling of the skin.It is also histologic  Read More

An accurate diagnosis is crucial to properly inform and counsel parents about epidermolytic hyperkeratosis or epidermolytic ichthyosis (EI). Prenatal diagnosis and genetic counseling are other options.Infection, secondary sepsis, and electrolyte imbalance are all heightened risks for newborns with epidermolytic ichthyosis who have denuded skin. The neonatal ICU should receive these infants so that it can monitor th  Read More

Most forms of erythropoietic protoporphyria are inherited.The risk factors of erythropoietic protoporphyria include:Porphyria can occur if you inherit a defective gene from one of your parents (autosomal dominant pattern) or inherit a defective gene from both parents (autosomal recessive pattern).Environmental factors may also trigger the development of signs and symptoms in porphyria.Trig  Read More

Skin peeling syndrome or familial continuous skin peeling happens on its own, is painless, and can last a lifetime while gradually getting better. Like skin peeling after a severe sunburn, affected people and/or their caretakers might frequently manually remove sheets of skin.Applying skin-softening (emollient) ointments to treat peeling skin syndrome, particularly after a bath when the skin is moist, may provide s  Read More

A genetic skin condition called hallopeau-siemens disease or dystrophic epidermolysis bullosa causes blisters to grow. One of the more severe types is the Hallopeau-Siemens syndrome type.Due to the defect's location in the dermis at the dermo-epidermal junction, even little skin trauma results in profuse blister production that always heals with scars.Anchoring fibrils are either absent or inadequate due t  Read More

Specific treatment for incontinentia pigmenti has not yet been described. However, the management of the disease requires a multidisciplinary approach and needs consultation with different specialists from time to time.Lesions appear within a few months from birth but disappear by adolescence. However, the lesions recur and require to be managed.All stage lesions must be kept cool and dry.The patients develop hypo  Read More

Localized Epidermolysis bullosa simplex (EBS) is a genetic disease, which means that it is caused by one or more genes not working correctly.The majority of EBS subtypes are inherited in a dominant manner. This means that an affected parent passes them on to half of his or her offspring. EBS affects both men and women equally.Epidermolysis bullosa simplex is often transmitted in an autosomal dominant manne  Read More

Non-scarring epidermolysis bullosa is a disease that results from mutations in KRT5 or KRT14 gene. These genes provide instructions for making a protein called keratin 5 and 14. There are two major types, and seventeen minor subtypes for this disease, all of which have common effects and symptoms.Among these, the four major subtypes of EBS are here:EBS-loc- in this, blisters are rarely present at birth and ma  Read More

UROD deficiency means a Lack of the enzyme uroporphyrinogen decarboxylase (UROD), which is a basic cause of porphyria cutanea tarda (PCT).This is a type of porphyria in which affected individuals are sensitive to sunlight. PCT is caused by a deficiency of UROD enzymes in the liver.There are three types of PCT that can be classified as type-1, type-2, and type-3.To cure these conditions, sunlight a  Read More