About lymphocytic infiltrate of jessner

What is lymphocytic infiltrate of jessner?

Jessner lymphocytic infiltrate of the skin is an uncommon disorder that is characterized by benign accumulations of lymph cells in the skin. These small lesions are solid, pink or red in color, and appear on the face, neck, and/or back. Skin surrounding these lesions may be itchy and turn red. The lesions may remain unchanged for several years and then spontaneously disappear, leaving no scars.

Not much is known about this disorder. In fact, there is some difference of opinion as to whether it is distinguishable as a separate condition or represents a stage of some other disorder. Some scientists believe that Jessner lymphocytic infiltrate may be a type of lupus erythematosus tumidus (LET) or discoid lupus erythematosus (DLE).

What are the symptoms for lymphocytic infiltrate of jessner?

Patients living with lymphocytic infiltrate of Jessner may experience symptoms including Itchiness (pruritus), Redness of the skin (erythema), and pimple-like eruptions (papules), most commonly on areas exposed to sunlight. These pimple-like Lesions may last up to several months. As they extend from the perimeter, these Lesions form well-defined, smooth, Red patches (plaques) whose diameter may go as far as up to one inch.

Occasionally, clear centers will form on the plaques. The skin surrounding the Lesions may be reddened or itching. Those affected may also experience a Burning sensation surrounding the skin lesions. An additional symptom that people with Jessner disease frequently report is sensitivity of the skin to sunlight exposure cutaneous photosensitivity.

The course of lymphocytic Infiltrate of Jessner varies from person to person. It is important to note that the symptoms typically disappear after several years but it is also possible that they may reappear later. The course or progression of the disease may alternate between periods of worsening and relieving of symptoms. These periods may last up to months or even years in some individuals.

What are the causes for lymphocytic infiltrate of jessner?

Lymphocytic Infiltrate of Jessner is a rare inflammatory disease with an unknown cause. What is known however is that this condition involves the inappropriate accumulation of T helper cells (subtype of white blood cells) in the skin. Some clinical scientists argue that this condition is possibly a subtype of the autoimmune condition known as lupus erythematosus, while others believe that it may have its own class.

Jessner disease may have a genetic/hereditary component. In addition, affected individuals may also have a prior history of photosensitivity.

What are the treatments for lymphocytic infiltrate of jessner?

Since lymphocytic Infiltrate of Jessner may sometimes resolve on its own, initial recommendation usually includes watchful waiting. In this case, treatment may not be necessary.

Others who may need to seek treatment might be advised to use cosmetics to improve appearance, protect from sunlight, removal of the lesions via surgery, radiotherapy, steroids including topical medium-potency formulations, freezing of the lesions (cryotherapy), the use of select oral medications, or appropriate chemotherapy drugs (cyclophosphamide, methotrexate).

It is important to note that the use of steroids, whether they be topical or systemic, must be monitored very closely. In addition, routine follow-up visits to the dermatologist are essential to monitor overall progress and treatment. Those seeking treatment must also remember to protect from sunlight to prevent progression of existing lesions or formation of new lesions.

What are the risk factors for lymphocytic infiltrate of jessner?

Lymphocytic infiltrate of jessner is a rare skin disorder characterized by non-scaly red areas and lumps on the face, neck, and upper back.

  • The lymphocytic infiltration of Jessner is considered to be related to the autoimmune disease lupus tumidus or discoid lupus erythematosus.
  • Other experts, however, argue that Jessner's lymphocytic infiltration should be classified as a separate entity.
  • Lymphocytic Infiltrate of Jessner is an uncommon inflammatory condition whose cause is unclear.
  • What is known is that this illness is caused by an abnormal buildup of T helper cells (a type of white blood cell) in the skin.
  • Some clinical scientists feel that this disorder is a subtype of the autoimmune disease lupus erythematosus, whereas others consider it a separate class.
  • Jessner disease may be caused by a genetic/hereditary factor. Furthermore, affected individuals may have a history of photosensitivity.
  • While its incidence in the United States or Europe is unknown, some scientists feel that lymphocytic infiltrate of Jessner is more common in men.
  • Furthermore, it usually appears between the ages of thirty and fifty, and it rarely affects children.


Symptoms
Itchiness,Redness of the skin,Pimple-like eruptions
Conditions
Papules,Erythema,Pruritus
Drugs
Hydrocortisone,Triamcinolone,Betamethasone,Pednisone, or antimalarials

Is there a cure/medications for lymphocytic infiltrate of jessner?

Lymphocytic Infiltrate of Jessner may sometimes resolve on its own; hence doctors may request the patients to wait and observe. In this case, treatment may not be necessary.

  • In severe cases, or the condition does not seem to resolve, medications may be prescribed accordingly.
  • In most cases, no therapy is required for Jessner lymphocytic infiltration.
  • Cosmetic camouflage can be used to conceal lesions and enhance one's appearance.
  • Removal of the lesions via surgery, radiotherapy, steroids including topical medium-potency formulations, freezing of the lesions (cryotherapy), the use of select oral medications, or appropriate chemotherapy drugs (cyclophosphamide, methotrexate) are among the treatments.


The following treatments have a varying response:

  • Corticosteroids, both topical and intralesional
  • Antimalarial drugs like hydroxychloroquine
  • Photochemotherapy or UVA1 phototherapy (PUVA)
  • Photodynamic treatment (PDT)
  • Cyclophosphamide
  • Thalidomide
  • Radiotherapy
  • Please note that the use of steroids (topical or oral) must be monitored carefully.
  • Routine follow-up visits to the dermatologist are essential to monitoring overall progress and treatment.


Symptoms
Itchiness,Redness of the skin,Pimple-like eruptions
Conditions
Papules,Erythema,Pruritus
Drugs
Hydrocortisone,Triamcinolone,Betamethasone,Pednisone, or antimalarials

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